Based on a recent study published in the British Medical Journal , commonly used ACE inhibitors are associated with a high risk of lung cancer in the adults.
In a large cohort study on 900,000 hypertensive adults who were treated for the first time between 1995 and 2015, lung cancer was diagnosed in 0.8% of the participants.
The authors note that ACE inhibitors lead to accumulation of bradykinin in the lungs, which “may directly stimulate growth of lung cancer.” A scientist also concludes, “In an individual patient, concerns about the long term risk of lung cancer should be balanced against gains in life expectancy associated with use of ACE inhibitors.”
However, this is a single study and further research is required to reach to a final conclusion.
The full text of this manuscript can be found here.